Nov 20, 2024 · Across 74 hospitals in seven countries, 3608 patients underwent randomization and were included in the intention-to-treat analysis; 1814 patients were assigned to 7 days of antibiotic treatment ...

Dec 4, 2024 · Sepsis, a syndrome of life-threatening, acute organ dysfunction due to a dysregulated response to infection, is a major global health burden. Worldwide, an estimated 48.9 million cases of sepsis ...

Dec 9, 2024 · Among the 390 enrolled patients, 194 were assigned to the daratumumab group and 196 to the active-monitoring group. With a median follow-up of 65.2 months, the risk of disease progression or death ...

Dec 31, 2024 · Highly pathogenic avian influenza (HPAI) A(H5N1) emerged in 1997. 1 Since then, it has spread globally by migratory birds, resulting in infections in animals on every continent. HPAI A(H5N1) clade ...

Nov 17, 2024 · A total of 7062 patients at 104 centers in 14 countries underwent randomization; at the time of analysis, the vital status was unknown for 45 patients (0.6%), and this information was most likely ...

The New England Journal of Medicine (NEJM) is a weekly general medical journal that publishes new medical research and review articles, and editorial opinion on a wide variety of topics of ...

Jan 1, 2025 · In 2020, an estimated 604,127 new cases of cervical cancer were reported worldwide, with 341,831 related deaths. 1 Low-resource regions of Latin America, sub-Saharan Africa, and Southeast Asia ...

Jan 8, 2025 · Heart failure with preserved ejection fraction is noted for symptoms of heart failure, LVEF of at least 50%, and cardiac or structural abnormalities. Treatment includes diuretics and SGLT2 inhibitors.

Dec 18, 2024 · Chronic venous insufficiency arises from a complex interplay of genetic predisposition; environmental factors, such as jobs that require prolonged standing or carrying heavy loads; and age-related ...

May 24, 2024 · We randomly assigned patients with type 2 diabetes and chronic kidney disease (defined by an estimated glomerular filtration rate [eGFR] of 50 to 75 ml per minute per 1.73 m 2 of body-surface area ...