Study highlights role of natural killer immune cell subsets in ALS Certain subsets of natural killer (NK) cells, a part of the immune system, were elevated in the blood of people with amyotrophic lateral sclerosis (ALS), where they showed altered gene activity and signaling patterns, a study found. One subset was associated with altered immune signaling, while another was linked…

Dec 30, 2024 · News stories about clinical trials testing potential treatments were among the top 10 most-read articles on ALS News Today in 2024.

MDA 2025: Cholesterol receptor ‘critical’ in sporadic ALS disease Signaling at the low-density lipoprotein receptor, known as LDLR, may be an important driver of neurodegeneration in sporadic amyotrophic lateral sclerosis (ALS), according to new preclinical research by U.S. scientists. In earlier work, the scientists discovered that mice injected with cerebrospinal fluid, or …

4 days ago · Scientists have developed a new method that can grow motor neurons from skin cells, which may serve as a platform for ALS cell therapies.

3 days ago · Certain subsets of natural killer (NK) cells, a part of the immune system, were elevated in the blood of people with amyotrophic lateral sclerosis (ALS), where they showed altered gene activity and signaling patterns, a study found.

Jan 8, 2025 · The number of ALS cases in the U.S. is expected to increase by over 10% by 2030, as compared with 2022 prevalence rates, per new study data.

6 days ago · A cholesterol receptor protein called LDLR appears to be a key driver of neurotoxicity in sporadic ALS, per new research using a mouse model.

5 days ago · Health Canada has invited Neurosense Therapeutics to discuss the potential for giving conditional approval to PrimeC in treating amyotrophic lateral sclerosis (ALS), according to a company filing with the U.S. Securities and Exchange Commission.

Jan 13, 2025 · An Alchemab-Eli Lilly partnership aims to identify new treatments for ALS based on antibodies from people with very slow disease progression.

Feb 13, 2025 · Fifteen nonprofit organizations across the U.S. formed a new ALS group, ALS United, to better address the needs of people living with amyotrophic lateral sclerosis (ALS) and drive advances in research toward better treatment options or a cure.