An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

Stress-related disorders stem from the interplay of genetic susceptibility and stress exposure, shaping gene and protein ...

This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators.

The diversity of post-transcriptional modifications during intervertebral disc degeneration • The development of therapeutic methods for spinal disease based on transcriptional and ...