Plants produce a wide diversity of compounds. Broadly, these are separated into primary metabolites, which are necessary for ...

Preterm birth can be severely harmful to neonates. Currently, no effective clinical treatments target in utero inflammation ...

Glucose levels influence physiology and adaptation rates under replication stress, yet core adaptive mutations remain ...

Prostate cancer (PCa) is the second most frequently occurring cancer and the fifth leading cause of cancer mortality among men worldwide in 2022 (Bray et al, 2024). Androgen receptor (AR) is ...

N6-methyladenosine (m 6 A) exerts many of its regulatory effects on eukaryotic mRNAs by recruiting cytoplasmic YT521-B homology-domain family (YTHDF) proteins. Here, we show that in Arabidopsis ...

Rheumatoid arthritis (RA) is associated with heart and lung dysfunction. Current therapies fail to attenuate such complications. Here, we identify formyl-peptide receptor type 2 (FPR2) as a ...

De novo protein design is of fundamental interest to synthetic biology, with a plethora of computational methods of various degrees of generality developed in recent years. Here, we introduce ...

Fungal infections and autoimmunity share a complex, bidirectional relationship that significantly impacts patient outcomes. Emerging evidence highlights how fungal pathogens contribute to autoimmune ...

Neural stem cell (NSC) function in mammalian brains declines during aging, but the molecular mechanisms involved remain ill-defined. Here, integrated multi-omics reveals continuous alterations of ...

Chloride (Cl −) ions cause major damage to crops in saline soils.Understanding the key factors that influence Cl − uptake and translocation will aid the breeding of more salt-tolerant crops. Here, ...

A previous study showed that the predominant macrophage population during the mid-stage of skin wound healing (3–5 days post-injury) expresses CD206 and can be further divided into CD301b-positive and ...

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