Researchers from Voyager Therapeutics Inc. presented preclinical activity data of VY-1706, a blood-brain barrier (BBB)-penetrant gene therapy comprising an adeno-associated virus serotype 9 capsid ...

RNA epigenetic modifications have uncovered as not only an intermediary structure between DNA and protein or an effector ...

RNA therapeutics market is expanding, driven by advancements in gene therapy, personalized medicine, and RNA-based drug delivery, along with rising research in mRNA vaccines, antisense ...

Atu027 (Silence Therapeutics) is yet another siRNA-based LNP formulation designed to knockdown ... LNPs, in turn, can effectively deliver miRNA therapeutics – alone or in combination – to treat solid ...

In a new study, researchers demonstrate that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria which downregulate gene expression of the mRNA ...

Department of Cardiovascular Medicine, The First Hospital of HeBei Medical University, Shijiazhuang 050031, Hebei Province, China Hebei Provincial Key Laboratory of Cardiac Injury Repair Mechanism ...

Circular RNAs (circRNAs) represent an abundant and conserved entity of non-coding RNAs; however, the principles of biogenesis are currently not fully understood. Here, we identify two factors, ...

Recent findings indicate that microRNA and RNA-decay pathways converge to the chromatoid body. This highly specialized structure might function as an intracellular focal domain that organizes and ...