The comedy duo were asked if they'd anticipated such a strong reaction to the premiere during a Comedy Central panel at San Diego Comic-Con.

Season 27 premiered Wednesday on Comedy Central with an episode titled "Sermon on the 'Mount" -- as in Paramount

Trey Parker and Matt Stone addressed controversy surrounding the "South Park" season 27 premiere depicting President Trump's penis while speaking at San Diego Comic-Con on Thursday.

The Trump administration responded to the scathing episode, which aired the same day Paramount announced a massive deal with the creators of “South Park.”

Following a near two-and-a-half-year hiatus, the premiere episode shows a naked Trump trying to seduce Satan, and came a day after the show's creators Trey Parker and Matt Stone had reached a $1.5 billion streaming deal with Paramount.

Comedy Central’s “South Park” recently struck a five-year deal with Paramount after a merger delayed the Season 27 premiere.

South Park” creators Trey Parker and Matt Stone hit the Comic-Con stage on Thursday night, a day after the Season 27 premiere of their smash Comedy Central series, “Sermon on the ‘Mount,” made waves for taking on both Donald Trump and “South Park’s” Paramount corporate parents.