SiRNA knockdown and indisulam treatment were used to study the ... Indeed while the initially list of approximately 2,000 enriched genes included important known factors like TLR3, TRIF, and UNC93B1, ...

Safety with the extended-duration small interfering RNA (siRNA) agent was favorable, with few adverse events reported. “Six decades after discovery of lipoprotein(a), finally advances in therapeutics ...

In this study, an innovative transdermal peptide, #PKU12, was developed based on transdermal peptide TD-1, and the anti-tumor effect of PKU12-based siRNA against HPV was investigated in vivo.