University of Pennsylvania researchers have developed a powerful new investigative tool to reveal how proteins work inside ...

A gene therapy recently approved by the FDA to treat patients with Sickle Cell Anemia is now being administered in St. Louis.

Vertex Pharma's £1.65 million ($2.05 million) gene-editing therapy for sickle cell disease (SCD), Casgevy, has been given the green light for use by the NHS in England under a managed access ...

A study of human tumor cells implanted in mice from the MacPherson Lab at Fred Hutch describes a new way to screen for the ...

STOP = Stroke Prevention Trial in Sickle Cell Anemia; SWITCH = Stroke With Transfusions Changing to Hydroxyurea; TCD = transcranial Doppler ultrasound Imaging of the aortic arch to the ...

"Sickle cell largely affects patients from African and African-Caribbean backgrounds, who are less likely to have a matching stem cell donor, and this community has been waiting years for a new ...

Apr. 25, 2025 — Chimpanzee naive pluripotent stem cells (PSCs) can now be grown in cellular cultures, reveals a recent study. They successfully created chimpanzee early embryo models, called ...

Disease-causing mutations in the signaling protein BMP4 impair its secretion, but only when it is made as a homodimer.

An ongoing, early-phase clinical trial of pociredir, an oral small molecule being developed by Fulcrum Therapeutics as a possible treatment for sickle cell disease (SCD), is still recruiting adult ...

Jennifer Lim, MD, FARVO, FASRS, discusses her ARVO presentation on sickle cell retinopathy, highlighting improvements in retinal surgery techniques and instrumentation. Joining the Eye Care Network in ...

Feb. 12, 2025 — Our cells constantly receive DNA damage from factors such as ultraviolet rays, irradiations, toxins and chemicals. For women, that can lead to poor egg quality, which in turn can ...