University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin ...

One protein mitigates Huntington’s disease while another one exacerbates it by regulating the huntingtin protein’s movement ...

University at Buffalo researchers shed some light on an enduring neuroscience mystery: How exactly does a mutated huntingtin protein (HTT) cause Huntington's disease?

Presymptomatic testing for Huntington disease (HD) has been available for ... it would have been interesting to know whether gender, overall pedigree size, number of affected individuals in ...

The study, published in Neuroepidemiology, confirmed northern Scotland has one of the highest rates of Huntington’s disease in the world at 14.5 per 100,000 people, more than five times the ...

Now, the researchers have learned more about what can control the traffic-controlling HTT.

They found that two specific signaling proteins, GSK3ß and ERK1, were expressed more in the neurons of Huntington’s disease patients, so they prevented them from functioning in the neurons of ...