Chronic liver disease gets worse when the liver's immune system stays overactive, resulting in ongoing inflammation and ...

Treg therapeutic designed to preferentially traffic towards its ligand CXCL12 over expressed in the bone marrow and spleen in myelofibrosis. -- CK0804 engages with antigen presenting cells within ...

The authors investigated the epigenetic mechanisms regulating the differentiation of circulating monocytes that infiltrate the CNS and adopt microglia-like characteristics. The work is useful to the ...

MLR may be a useful marker for assessing activity and progression in chronic lymphocytic leukemia (CLL). Patients with CLL had significantly lower MLR values compared to healthy individuals, with ...

Atrial fibrillation (AF) is increasing in prevalence and linked to higher morbidity and mortality rates. Emerging evidence implicates inflammation as a key driver of AF pathogenesis. 1 Our study aimed ...

Introduction: Tumor-associated macrophages (TAMs) recruited from circulating monocytes drive tumor-growth and establish an immunosuppressive tumor microenvironment (TME). Initial events in transition ...

It’s one thing to find a pair of kicks that feel comfy, but it’s an entirely different, better thing to come upon some that truly fit your feet—from the length to the width to the arch. As challenging ...

Monocytes are heterogeneous immune cells that play a crucial role in the inflammatory response during atherosclerosis, influencing the progression and outcome of the disease. In the pathogenesis of ...

Maddy has a degree in biochemistry from the University of York and specializes in reporting on health, medicine, and genetics. Maddy has a degree in biochemistry from the University of York and ...

New research reveals insight into the impact sleep quality has on a person's immune system, and how it could be linked to the development of diseases such as obesity, diabetes, and cardiovascular ...