Like Jakafi, momelotinib is a JAK1/2 inhibitor, treating symptoms of the cancer, but also targets other pathways called ACVR1 and IRAK1 that are thought to protect against red blood cell destruction.

Sobi said the selective JAK2, IRAK1, and ACRV1 inhibitor will slot into its haematology portfolio alongside Doptelet (avatrombopag), an oral thrombopoietin receptor agonist for primary chronic ...

At close: 11 April at 16:00:00 GMT-4 ...