GSK's clinical-stage pipeline is currently focused on oncology, respiratory, immunology and inflammation, and infectious ...

The U.S. Food and Drug Administration approved treatment for 11 patients with the rare familial ALS caused by mutations in ...

Typically, LNPs contain four main lipid components: ionizable lipid that binds to the negatively charged RNA and assists in endosomal escape ... with dose-dependent increases in siRNA antisense strand ...

Each antibody produced by your immune system binds to a specific antigen and then either destroys the pathogen or tags it so other immune cells will recognize it. Antibodies are also known as ...

Discover how RNA therapeutics are reshaping medicine, offering new treatments for previously undruggable targets.

For transcription, a solution containing 2 μM of the double-stranded DNA, 6.25 mM rNTP, 80 mM HEPES-KOH pH 7.5, 24 mM MgCl 2, 2 mM spermidine, 40 mM DTT, 20 μg/mL pyrophosphatase (Roche) and a ...

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions like a film editor rearranging scenes from the same footage to create ...

I was pressing the left and the right arrow in this example. Since: 0.1.8 Binds will repeat by default (i.e. holding down a bind will make it trigger repeatedly). You can disable that for specific ...

WICHITA, Kan. – When building a list of the best high school basketball teams in recent memory, it’d be easy to make a case for two teams from Florida-based Montverde Academy. The prep ...

They found their answer in antisense oligonucleotides (ASOs ... "It likely sequesters other RNA-binding proteins, creating an even more toxic environment for cancer cells." ...