with a JAK1-targeting siRNA-lipid conjugate. For the initial indication, it is formulated as an intradermal injectable. Alys is also developing a trans-epidermal formulation of ALY-101 ...

The uniqueness of the DRB4D3 structure implies that the trans-acting (tasi)/siRNA initiation complex formed by DCL4:DRB4 in plants is diverse from its non-plant higher eukaryotes. Overall, we present ...

Cells were treated for 6 hr with DMSO, TG or OSMI-1 3 days after siRNA treatment. The blot was probed for GFP as above. To screen for trans-acting factors that regulate OGT intron retention, we ...

Monica Forrester remembers her friend, Chevranna Abdi, as someone well known to step up to help other trans women ... of a woman "wielding a knife and acting in a bizarre fashion." ...

The same day Vivian Jenna Wilson, Elon Musk’s estranged daughter, published her second-ever interview with a media outlet, the billionaire media mogul used his X platform to insinuate trans ...

“My wife is the best, and I have a new puppy,” I responded, taking his cue. Also, I am trans and an immigrant. Personally. My father, my children, my wife and my closest friends are ...

Surgery is an option that some, but not all, trans people choose as a part of the broader gender-affirming care they may receive to help them with their transition. Ashton was 19 at the time.

Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window CHICAGO -- Novel small interfering RNA (siRNA) agent lepodisiran drastically cut levels of lipoprotein(a), or Lp(a), in ...

I know the whole industry stopped, but what do you recommend?" She was like, "Hey, you should try out voice acting." I've been hearing since I was young that I sounded like a 40-year-old man.