Fig. 1 | The NLRP3 inflammasome is an upstream activator of IL-1β and IL-18. NodThera is employing novel chemistry to create small molecules that inhibit the NLRP3 inflammasome that have now ...

Treatment with the fully brain-penetrating NLRP3 inflammasome inhibitor also sharply limited weight regain following the cessation of semaglutide therapy and reduced multiple cardiovascular, ...