Nerve cells are not just nerve cells. Depending on how finely we distinguish, there are several hundred to several thousand ...

Each stem cell sends a branch upward through the layers of cortex, and this extension acts like a guide wire for newborn neurons traveling through the cortical layers. “There is a whole region that’s ...

The cerebral cortex, the largest and most complex component of the brain, is unique to mammals and alone has evolved human specializations. Although at first all stem cells in charge of building ...

Researchers at UCSF have succeeded in mapping the genetic signature of a unique group of stem cells in the human brain that seem to generate most of the neurons in our massive cerebral cortex.

Efforts to study the development and function of the human cerebral cortex in health and disease have been limited by the availability of model systems. Extrapolating from our understanding of ...

The new work takes two distinct approaches to getting stem cells to form a more organized cortex. The first involves the culture conditions. Rather than growing them in a dish or a gel, the ...

Researchers at UCSF have succeeded in mapping the genetic signature of a unique group of stem cells in the human brain that seem to generate most of the neurons in our massive cerebral cortex.

Stem and progenitor cells exhibit diversity in early brain development that likely contributes to later neural complexity in the adult cerebral cortex, according to a new study.

Researchers have used human neural stem cells to 3D print functional brain tissue that mimics the architecture of the cerebral cortex, the brain’s outermost layer. The breakthrough technique has ...

"These stem cell-derived neurons can grow nerve fibers between the brain's cerebral cortex and the spinal cord, so this study confirms the use of stem cells for therapeutic goals," the research ...