1 Dalian Key Laboratory of Chronic Disease Research Center, Dalian University, Dalian, Liaoning, China 2 Tangshan Seventh Hospital, Tangshan, Hebei, China Alcoholic liver fibrosis (ALF) developed from ...

Integrated analysis of ChIP-seq, ATAC-seq and RNA-seq recognized that SIRT1 was the key gene affected by IDH1 deficiency. Thus, our current work provided novel insights for further clarifying ...

Mito-TEMPO (SML0737) and crystal violet (C0775) were purchased from Sigma-Aldrich (Schaffhausen, Switzerland). Sirt3 siRNA (SC61555), and control siRNA (SC36869) were purchased from Santa Cruz ...

Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No. 100 Haining Road, Shanghai 200080, China Department of Gastric Surgery, Cancer Hospital of ...

ECs were seeded and transfected with deacetylase sirtuin-1 (SIRT1) small interfering (siRNA) (20 nM; Qiagen, Hilden, Germany) or control siRNA (20 nM). Adenovirus amplification (gift from Dr ...

Mechanistically, we show that LMOD1 physically and functionally interacts with the deacetylase sirtuin1 (SIRT1), a regulator of myogenic differentiation, especially at the onset of myogenic ...