This manuscript characterizes a mutated clone of RNA polymerase I in yeast, referred to as SuperPol, to understand the mechanisms of RNA polymerase I elongation and termination. The authors present ...

Stress-related disorders stem from the interplay of genetic susceptibility and stress exposure, shaping gene and protein ...

This discovery, facilitated by the metabolic carbohydrate reporter per-O-acetylated N-azidoacetyl-mannosamine, underscores the potential for biological roles of previously unknown RNA modifications ..

The diversity of post-transcriptional modifications during intervertebral disc degeneration • The development of therapeutic methods for spinal disease based on transcriptional and ...