Stress-related disorders stem from the interplay of genetic susceptibility and stress exposure, shaping gene and protein ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

16 The emerging epitranscriptomic field features a multitude of post-transcriptional modifications with the potential to affect gene expression by impacting RNA localization, stability ...

In recent years, the development of sophisticated methodologies based on second- and third-generation sequencing has enabled the RNA community to explore ...

14–26A→G), we initially explored two possible mechanisms: the modification of EPO isoforms ... we explored a third hypothesis involving transcriptional dysregulation induced by these variants.

The diversity of post-transcriptional modifications during intervertebral disc degeneration • The development of therapeutic methods for spinal disease based on transcriptional and ...

Following post-transcriptional modifications by distinct combinations of human pseudouridine synthases, we find that tRNAs become stabilized and undergo specific local structural changes. We establish ...

The role of EGFR in KRASG12D-driven tumorigenesis was studied using mouse CRC organoids with KRAS-APC-TP53 mutations and ...