Scientists insert variable DNA sequences coding for their proteins of interest into plasmids that carry a phage coat protein gene, an antibiotic resistance gene, and a packaging signal. Then they ...

Biliary tract infections (BTI), often linked to structural abnormalities like bile duct stones, pose significant treatment challenges due to drug-resistant bacteria like Pseudomonas aeruginosa. Phage ...

Bacteria, which are susceptible to infection by bacteriophages, often carry multiple genes encoding anti-phage defense ...

In a new study, a team from The Ohio State University has reported on the molecular assembly of one of the most common ...

All bacteriophages are composed of a nucleic acid molecule that is surrounded by a protein structure. A bacteriophage attaches itself to a susceptible bacterium and infects the host cell.

In this issue, Gishizky and coworkers describe yet another use for phage display—a method for mapping protein–protein interactions that is faster than two-hybrid systems and that allows the ...

In a recent study, however, Yale scientists describe a new method for quantifying the host-attachment dynamics of several phage species—including some that target key bacterial pathogens ...

Phage therapy exploits the fact that bacteriophages ... prediction of Staphylococcus aureus phages through receptor-binding ...

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particularly a ubiquitin-like protein,” said Corbett. To understand how Bil works, Sorek’s team compared phage progeny from infected bacteria with and without the system. They performed density ...

If Pnkp and Rnl1 are not present, depletion of the pool of functional tRNA Lys by PrrC blocks phage protein synthesis and arrests the infection before it can spread. However, Pnkp and Rnl1 repair the ...

In the fight against antimicrobial-resistant (AMR) superbugs, an important weapon may just be hiding in some polluted stream, ...