Scientists insert variable DNA sequences coding for their proteins of interest into plasmids that carry a phage coat protein gene, an antibiotic resistance gene, and a packaging signal. Then they ...

In answering these questions and to understand how phages transform Streptococcus into a deadly pathogen, Dr. Gerd Prehna and his lab have been studying the phage protein paratox (Prx).

Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades. In a new study, ...

Bacteria, which are susceptible to infection by bacteriophages, often carry multiple genes encoding anti-phage defense ...

Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades. In a new study, researchers show that the emergence of resistance can be understood in the ...

Biliary tract infections (BTI), often linked to structural abnormalities like bile duct stones, pose significant treatment challenges due to drug-resistant bacteria like Pseudomonas aeruginosa. Phage ...

In this issue, Gishizky and coworkers describe yet another use for phage display—a method for mapping protein–protein interactions that is faster than two-hybrid systems and that allows the ...

If you're interested in participating in the phage research course, we encourage you to apply! Please also ask a teacher to fill out our easy recommendation form (no formal letter of recommendation ...

particularly a ubiquitin-like protein,” said Corbett. To understand how Bil works, Sorek’s team compared phage progeny from infected bacteria with and without the system. They performed density ...

Filamentous bacteriophage fd can display multiple copies of foreign peptides in the N-terminal region of its major coat protein pVIII, 2,700 copies of which make up the virus capsid. Here we show ...

If Pnkp and Rnl1 are not present, depletion of the pool of functional tRNA Lys by PrrC blocks phage protein synthesis and arrests the infection before it can spread. However, Pnkp and Rnl1 repair the ...

This important study analyzes the effect of heat treatment on phage-bacterial interactions and convincingly shows that prior heat exposure alters the bacterial cell envelope, enhancing persistence and ...