Kefir, a probiotic-rich fermented milk, shows potential in reducing neuroinflammation, oxidative stress, and beta-amyloid ...

At present, plenty of drugs targeting NLRP3 inflammasome have been proved to have a good effect on metabolic diseases, such as Anakinra (IL-1 receptor antagonist) and Atorvastatin (inhibits TLR4/MyD88 ...

ENaC, epithelial sodium channel; NLRP3, NLR family pyrin domain containing 3; NF-κB, Nuclear factor kappa-light-chain-enhancer of activated B-cells; MyD88, Myeloid differentiation primary response 88; ...

Host cells activate cell death pathways in response to bacterial manipulation of innate immune signalling, but the molecular ...

Eighty percent of patients with relapsed or refractory Waldenstrom’s macroglobulinemia responded to treatment with iopofosine I 131, researchers found. A small study of iopofosine I 131 in patients ...

Herpesvirus-encoded microRNAs (v-miRNAs) play a crucial role in modulating host cellular processes to promote viral persistence, immune evasion, and pathogenesis. These v-miRNAs function by targeting ...

Neuroinflammation significantly contributes to stroke pathophysiology, leading to tissue damage and neurological deficits. Baicalein, a potent 12/15-LOX (12/15-lipoxygenase) inhibitor, demonstrates ...

Division of Infectious Diseases and Immunology, Department of Pediatrics, Guerin Children’s at Cedars-Sinai Medical Center, Los Angeles, CA (P.K.J., D.W., A.C.G., T ...