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Researchers conducted a study on medications used in psychiatry and neurology during the perinatal period, assessing how ...
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News-Medical.Net on MSNExploring drug absorption models through particle size, dose, and confinementThe traditional film model for particle dissolution assumes that flux behavior depends primarily on particle size relative to ...
However, their strong hydrophilicity and poor lipophilicity result in insufficient cell membrane permeability, and high doses are required to achieve therapeutic effects, which severely limits ...
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News-Medical.Net on MSNAssessing the impact of the particle drift effect on oral drug absorption using flux toolsDiscover how particle drift analysis using flux tools improves oral drug absorption in pharmaceutical research.
Moreover, cyclic peptides exhibit strong lipophilicity, making them less likely to penetrate the intestinal epithelium and more suitable for intestine-targeted drug development. Their inherent ...
In the field of medicinal chemistry, heterocyclic compounds play an essential role by displaying different biological activity. Five-membered ring containing heterocycles always attracted researchers ...
Moreover, cyclic peptides exhibit strong lipophilicity, making them less likely to penetrate the intestinal epithelium and more suitable for intestine-targeted drug development. Their inherent ...
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