Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to a high risk of bowel cancer, also a greatly increased risk of duodenal cancer.

The global burden of chronic kidney disease (CKD) is rising, with more than 800 million people affected worldwide. Vascular diseases in patients with CKD are unique and grouped as uremic vascular ...

This study presents a valuable finding on the direct cytotoxic effects of DuoHexaBody-CD37 in diffuse large B-cell lymphoma, mediated via SHP-1 activation and antibody clustering, independent of ...

FDA clears Nurix Therapeutics, Inc.'s GS-6791 for inflammatory disorders; Nurix earns $5M milestone from Gilead. Click for my ...

The risk for inflammatory bowel disease is higher in patients with psoriasis or ankylosing spondylitis using IL-17A inhibitors than in those using apremilast, necessitating careful patient monitoring.

is set to host the Global Pathway Expo 2025 on 17 April at its Gulshan-2 office in Dhaka. The expo aims to connect aspiring students with representatives from leading universities in the UK, USA, ...

In addition, CM can also regulate the expression and signaling pathway of IL-17, further inhibit inflammatory response and improve the symptoms of CHD, providing a new idea and method for the ...

In a 2019 study in mice, Choi and Huh showed that in some cases of infection, IL-17 is released and suppresses a small region of the brain's cortex known as S1DZ. Overactivation of neurons in this ...

Summary: New research reveals that the immune molecule IL-17 can influence behavior by acting directly on specific regions of the brain. IL-17 reduces neuron excitability in the cortex to enhance ...

Future comprehensive studies should focus on developing more physiologically relevant models to clarify IL-17-mediated signaling pathway in specific cells types at different stages of human chronic ...