Primary efficacy measures yielded pain scores, which were analysed with repeated measures analysis of variance (ANOVA), and patient preference was analysed with a goodness-of-fit chi 2 test.

The Hosmer‒Lemeshow test showed that the model had satisfactory goodness of fit (χ 2 = 10.757 ... Differences were explored using the Chi-square test or Fisher’s exact test for categorical variables ...