AI is enabling the development of a next generation of drugs that can more precisely target cancer cells while sparing ...

Cytochrome P450 (CYP) proteins are responsible for breaking down more than 80% of all Food and Drug Administration ...

Scientists have designed new drug frameworks that selectively target CYP3A4, one of the most critical CYP proteins.

Millions of individuals rely on effective medications to manage diseases like cancer and diabetes. For those with chronic myeloid leukemia (CML), advancements in treatment selection could ...

India lacks a dedicated early warning system for detecting and responding to emerging drug threats like NPS or synthetic opioids such as Nitazenes. Existing frameworks focus more on reducing the ...

[27] Unfortunately, the placebo effect was marked, showing a minimal drug-placebo difference with yohimbine given at a dose of 5.4mg 3 times daily. Yohimbine is also available in lower potency ...

The findings suggest that the dimerized form of THIO could enhance chemotherapeutic efficacy by effectively targeting GSTP1 and reducing drug resistance ... and inhibitory potency of this novel ...

In light of claims of improved efficacy and lower incidence of adverse ... drug haloperidol in 95 studies, and the low-potency drug chlorpromazine in 28 studies, with the remaining studies using ...

However, the first-generation drugs targeting PI3Kα inhibit the wild-type and mutant PI3Kα with equal potency, which raises concerns of tolerability and therapeutic efficacy. As a novel ...

The aim of this review is to summarize the data on the efficacy and safety of inhaled anticholinergic drugs in asthma, and to propose a possible use of these drugs in asthma management.

Research reveals significant differences in how supplements are manufactured, tested, and regulated—differences that can impact both safety and efficacy. While all supplements fall under less ...