The aim was to discover new nucleotides that would work in the DNA structure and could be usefully distinguished using the single-strand DNA reading equipment created by UK-based Oxford Nanopore – in ...

A) DNA polymerase binds to a single-stranded DNA template (blue) and synthesizes a complementary strand of DNA (red). B) When DNA polymerase randomly incorporates a fluorescently labeled ddNTP ...

DSBs can be repaired using several different mechanisms. Both ends can be simply rejoined with little or no further processing (nonhomologous end joining, or NHEJ) or can be repaired using ...