Latest study leverages new constructs for nuclear localization signal (NLS) sequences to improve editing efficiency in human immune cells.

The CRISPR revolution started in 2012 ... which has the ability to unwind the DNA double helix and then move along the DNA strand. "This 'long-distance' silencing mechanism is different from ...

Most cells in the human body each contain about six feet of DNA. Yet the nucleus, where DNA is coiled, is no larger than a ...

Gene editing and many other useful biotechnology tools came from studies of bacteria fighting off viral invaders. But ...

Even CRISPR-Cas9, the groundbreaking technology that earned a Nobel Prize in 2020, has major limitations. It cuts both strands of the DNA helix, making it most useful to disrupt rather than correct ...

The incidence of Human Papillomavirus (HPV)–associated oropharyngeal cancers—tumors of the back of the mouth and throat—is ...

A team discovers a new family of enzymes capable of inducing targeted cuts in single-stranded DNA A few years ago, the advent of technology known as CRISPR was a major breakthrough in the scientific ...

Gene editing technologies allow scientists to use enzymes -- in this case, Cas9 (CRISPR-associated protein 9) -- as a sort of molecular scissors that can precisely cut or modify portions of DNA or ...

A revolution is underway in gene editing -- and at its forefront is David Liu, an American molecular biologist whose ...

The researchers analyzed changes to gene expression in ecDNA formed by HPV and human DNA hybridization in oropharyngeal tumor ...

Gene editing technologies allow scientists to use enzymes—in this case, Cas9 (CRISPR-associated protein 9)—as a sort of molecular scissors that can precisely cut or modify portions of DNA or ...

Even CRISPR-Cas9, the groundbreaking technology that earned a Nobel Prize in 2020, has major limitations. It cuts both strands of the DNA helix, making it most useful to disrupt rather than ...