who demonstrated that TLR9 is absolutely required for all cellular responses to CpG DNA 2. The authors have shown that cells derived from TLR9-deficient mice are unresponsive to CpG stimulation.
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Nucleic acid drug iSN40 shows promise for osteoporosis treatmentMore information: Rena Ikeda et al, Osteogenic CpG Oligodeoxynucleotide, iSN40, Inhibits Osteoclastogenesis in a TLR9-Dependent Manner, Life (2024). DOI: 10.3390/life14121572 ...
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Complex interactions between nucleic acid sensors and enzymes in immune cells explainedADA2, previously known for its role in catalyzing the deamination of adenosine to inosine, is revealed to function as an ...
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