People with type 2 diabetes treated with metformin plus a sulfonylurea with high affinity for cardiac mitochondrial adenosine triphosphate–sensitive potassium (mitoK ATP) channels, such as glyburide ...

Background and goal: Sulfonylureas are a class of oral medications used to manage blood glucose levels in patients with type 2 diabetes. These drugs increase insulin production regardless of blood ...

Background: A 12-week-old female presented with neonatal diabetes. Insulin therapy alleviated the diabetes, but the patient showed marked motor and mental developmental delay. The patient underwent ...

In a study from Korea, adults with type 2 diabetes had a lower risk for autoimmune rheumatic diseases after starting an SGLT2 inhibitor rather than a sulfonylurea. Over 15,000 adults would need to be ...

Among adults with type 2 diabetes who started noninsulin second-line therapy, most modified treatment within 1 year. Discontinuation was by far the most common modification. Objectives: To describe ...

The diabetes drug glipizide was linked to a higher risk of serious heart problems compared to dipeptidyl peptidase-4, or DPP4, inhibitors in patients with Type 2 diabetes, according to a study ...

For many living with type 2 diabetes, managing blood sugar is a daily reality. Often, medications come as a lifeline, and among them, sulfonylureas like glipizide are popular choices, especially in ...

Pregnant women with gestational diabetes had worse outcomes with glyburide. Glyburide is associated with an increased risk of adverse neonatal outcomes compared to insulin in women with gestational ...