Recent publications analyzing the relationship between local free energy and siRNA efficiency 4,5 have demonstrated that mRNA target site secondary structure is of great importance for siRNA ...

Researchers have shown, for the first time, how the genetic material of the Nipah virus replicates in infected cells. The virus can cause fatal encephalitis in humans.

Evidence has also shown that siRNA is involved in antiviral defense in certain plant and animal species. Plants are able to fight viral infection by using the viral ssRNA to generate dsRNA ...