RNA epigenetic modifications have uncovered as not only an intermediary structure between DNA and protein or an effector ...

By the early 1990s, scientists thought that they understood the basic principles of gene regulation, but then a series of unusual findings emerged. “At the time, there was no framework for thinking ...

BIIB080 is an antisense oligonucleotide therapy designed to target microtubule-associated protein tau mRNA and reduce the production of tau.

That Anabel was able to figure out this novel transcriptional regulation mechanism ... translation of a divergent upstream gene by modulating antisense RNA production, Proceedings of the National ...

Efficient RNA interference in Caenorhabditis elegans ... exogenous RNAi-induced silencing and their roles in endogenous gene regulation. Although it is too early to assess whether secondary ...

This form of gene regulation is observed across a broad ... For instance, HOX antisense intergenic RNA (HOTAIR) is a lncRNA ...

RNA therapeutics market is expanding, driven by advancements in gene therapy, personalized medicine, and RNA-based drug delivery, along with rising research in mRNA vaccines, antisense ...

BIIB080 is an investigational antisense oligonucleotide therapy that targets microtubule-associated protein tau mRNA preventing the production of the disease-causing protein. The Fast Track ...