A precision medicine workflow integrating proteomics and personalized xenograft models was developed and applied to an ...

The complexity of the TME in vivo limits the conclusions that can be drawn from in vivo models. Optimizing cell culture ...

Using single-cell RNA sequencing, they have analyzed tumor tissues ... to expand the platform to model metastatic disease in neuroblastoma and create patient-derived xenograft (PDX) organoids.

The management of breast cancer involves various therapeutic approaches. However, many current anticancer treatments indiscriminately damage both cancerous and healthy cells. In cancer treatment, ...

Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients with RAS/MAPK ...

Hoth Therapeutics (HOTH) announced breakthrough preclinical findings demonstrating the efficacy of HT-KIT, a novel targeted therapy for ...

Expression data from patient-derived xenograft (PDX) mouse models exposed to micvotabart pelidotin (MICVO) indicate gene signatures associated ...

SIL204 cut tumor cell numbers by ~70% in AsPC-1 and ... showed significant efficacy in orthotopic xenograft models where tumors grow in their native pancreatic environment, representing a more ...

Data presented at European Molecular Imaging Meeting (EMIM 2025) for imaging with 68Ga-RAD202 confirms specific accumulation in the tumor, favorable biodistribution and low uptake in non-target organs ...