Gene editing and many other useful biotechnology tools came from studies of bacteria fighting off viral invaders. But ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system ... from the well-known type II CRISPR systems like Cas9.

Scientists have categorized different types of CRISPR systems into two classes based on how their Cas nucleases function ... for CRISPR-mediated genetic manipulation. (2) Researchers deliver CRISPR ...

Yet others, called base editors, change one letter of the DNA code to another. So why do we call it CRISPR? Cas proteins are used by bacteria to destroy viral DNA. They add bits of viral DNA to ...

CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a ... Here, the authors report compact type V-K CAST discovered from genome-resolved metagenomics and demonstrate ...

New CRISPR-Cas systems have been identified, enhancing the gene editing toolkit. A notable system, SubCas9, from bacteria in dairy cows, is efficient, small, and can target unique gene sequences ...