Toll-like receptors (TLR) make the first contact with invading bacteria and function as sensors of infection for immune cells. But the signalling pathway is apparently identical for all TLRs and it is ...

Researchers from The University of Osaka find that chronic liver congestion is linked to severe liver diseases through a specific signaling pathway in liver sinusoidal endothelial cells - key cells ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...