Toll-like receptors (TLR) make the first contact with invading bacteria and function as sensors of infection for immune cells. But the signalling pathway is apparently identical for all TLRs and it is ...

Ischemic stroke is a complex cerebrovascular disorder characterized by highly unpredictable outcomes influenced by ...

Cellular death within the infarcted core occurs rapidly due to energy depletion, resulting in the release of DAMPs such as ...

Researchers have identified a cell signaling pathway involved in the development of Barrett’s esophagus and esophageal adenocarcinoma, which may lead to possible life-saving therapy for this ...

A tissue section from a mouse model of lung metastasis showing cancer cells (green) that have attracted and activated fibroblasts (red) to support the growth of a metastatic tumor. Image: Massagué Lab ...