Tetrodotoxin (TTX) is best known as the neurotoxin of the puffer fish, though it also appears in a range of other marine species. You might remember it from an episode of The Simpsons involving a ...

Think about walking into a restaurant and ordering a meal where just one microscopic mistake in preparation could put you six ...

Opioids remain a mainstay of treatment for chronic and surgical pain, despite their side effects and risk for addiction and overdose. While conventional local anesthetics block pain very effectively, ...

Pufferfish are famous for containing one of the most potent natural toxins known: tetrodotoxin. But what would happen if a massive whale swallowed a poisonous pufferfish? This video dives into the ...

The neurotoxin tetrodotoxin has been found for the first time in two species living out of water. Tetrodotoxin is a potent paralysis-inducing neurotoxin found in a multitude of aquatic organisms, but ...

The poison found in pufferfish, blowfish, balloon fish, toads, sunfish, porcupine fish, toadfish, globefish, and swellfish is a tetrodotoxin. This is one of the most toxic poisons found in nature.

A quicker way of making one of the world’s most potent neurotoxins could lead to novel drugs for pain relief and to a better understanding of how the body’s pain system works. Tetrodotoxin (or TTX) is ...

Some newts living in the western United States are poisonous, perhaps thanks to bacteria living on their skin. Tetrodotoxin, or TTX, prevents nerve cells from sending signals that tell muscles to move ...

Cancer is awful. And treatments for cancer, including chemotherapy, can be incredibly painful. Even the treatments for the pain, usually opioids like morphine, can be debilitating, with side effects ...

Alternatives to opioids for treating pain are sorely needed. A study in rats suggests that tetrodotoxin, properly packaged, offers a potentially safe pain block. Opioids remain a mainstay of treatment ...