“Neuropeptide signaling orchestrates T cell differentiation.” How would you summarize your study for a lay audience? T helper (TH) cells are essential immune cells that help other immune cells ...

The creation of these fighting cells requires new programming of CD8 + T cells, a process known as differentiation. Previous work by the team had shown that the NOTCH signaling pathway played a ...

In addition, IL-6 blockade has been shown to attenuate disease activity in several models of autoimmune disease, presumably via the suppression of T-helper-17 cell differentiation and IL-17 secretion.