One explanation for phasing is that only one secondary siRNA is made per round. Possible routes for such synthesis are self-termination of RdRP activity, or more processive RdRP activity coupled ...

In SNALPs, the backbone-modified siRNA is encapsulated within a closed shell of a cationic-zwitterionic lipid bilayer, furnished with an outer PEG shield (Figure 2A). The lipid bilayer contains a ...

A live webcast of the event will be available in the Investor Relations secti —Becomes first company to showcase four routes of synthesis for approved siRNA therapeutic asset— —Joint poster ...

Represents first project to enter the ECO Synthesis™ Innovation Lab Core enzymes for ECO Synthesis™ technology have transitioned from research into development and scale-up as the first step in ...

Codexis expects to achieve pilot scale production of GLP-grade siRNA material using the ECO Synthesis™ Innovation Lab in 2025. The Company anticipates hosting presentations at the 2025 TIDES USA ...

Our goal is ambitious: scaling our siRNA platform and accelerating recent technical progress in the synthesis of high-purity guide RNA for gene editing. We expect several key announcements this ...

Codexis shares were 20% higher, at $3.07, after the company recorded its first revenue-generating contract to manufacture siRNA material in its ECO Synthesis Innovation Lab.

In this study, the authors demonstrated that exosomes can serve as delivery vehicles to introduce AGO2-loaded siRNA into the cytoplasm of bacteria, and in turn down-regulated gene expression of ...

Codexis (CDXS) announced its first revenue-generating contract to manufacture siRNA material in its ECO Synthesis Innovation Lab. Codexis has ...

Codexis intends to sign its first development contract for its ECO Synthesis™ manufacturing services in the first half of 2025. Codexis expects to achieve pilot scale production of GLP-grade siRNA ...