Understanding APOE and its variants All humans ... An mRNA transcript is a nucleotide sequence formed during alternative splicing to create a protein. Variations in how RNA segments come together ...

The simplest way to decipher the code would be to start with an mRNA molecule of known sequence, use it to direct the synthesis of a protein, and then determine the amino acid sequence of the ...

Putting these individual elements together creates a collective unique signature, which lets us adopt a fingerprint-based approach and use a signature to identify a protein. These sequence differences ...