Caption: Structure of a HIV capsid (Left) Central slice view of a HIV virus-like particle with pore-forming toxin on the membrane (Middle) Atomic model of a HIV capsid (Right) Density map of HIV ...

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The C-terminal part of A2 extends through the central pore of the B pentamer, and is linked noncovalently to the B-subunits. Intracellularly active toxins can ... that form a symmetrical ring ...

When bound to the receptor, toxins can act at the cell membrane by interfering with signal transduction pathways, pore formation or enzymatic activities on membrane compounds. Various enterotoxins ...