Hydrolysis, or peptide bond cleavage via reaction with water, is theorized to be a primary degradation mechanism, particularly in aqueous solutions. Acidic or basic conditions may accelerate this ...

Peptide bonds are formed by a biochemical reaction that extracts a water molecule as it joins the amino group of one amino acid to the carboxyl group of a neighboring amino acid. The linear ...

This interaction involves the sharing of electrons between neighboring peptide bonds, which keeps water molecules from breaking the bonds and triggering hydrolysis. This is a chemical reaction in ...

Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids within proteins (known as proteolysis). Proteases can also remove protein post ...