The validation of this pathway has in large part been a result ... Early positive trials testing the efficacy of IL-17 blockade in key inflammatory diseases similar to psoriasis, as well as ...

This collection of Research and Review-type articles highlights the role of the IL-17 pathway in inflammatory diseases, and how our improved understanding of the mechanisms of disease has revealed ...

To further explore the contribution of the IL-6–IL-17 pathway in polymyositis, Kohsaka et al. injected B6 mice lacking either IL-6 or IL-17A with recombinant C-protein. As their previous study ...