or sometimes by switching off the gene altogether to see what happens if it doesn’t work (these are called knockout mice, and they’re a staple of medical lab research). In 2013, researchers in ...

The Ca2+ stored in the cellular endoplasmic reticulum (ER) plays a crucial role in protein folding and lipid transfer, and its impairment leads to cellular ER stress. When chronic cellular ER stress ...

Trump misstated $8 million spent on transgender mice, sparking debate on transgenic research and its importance in science.

Colossal Biosciences leaders say the fluffy, golden-haired mice help validate their technique to “de-extinct” species, but outside scientists remain skeptical ...

However, the role of the Nwd1 gene in SERCA2 activity and the ... The team created an Nwd1 knockout (Nwd1 −/−) mice model ...

A research team led by Prof. Zhang Xin from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences has revealed how magnetic properties in mice vary under different physiological ...

The team then edited the mouse genome using a streamlined strategy that combined three editing technologies: RNP-mediated knockout ... to modify seven genes. The gene editing resulted in mice ...

By replacing the defective gene associated with Dravet syndrome in mice, scientists successfully alleviated symptoms without ...

A one-time injection of a novel gene therapy was able to save mice and a newborn calf from succumbing to maple syrup urine disease (MSUD), suggesting the approach could one day be used to treat ...

Study highlights the role of the Nwd1 gene in liver disease, paving the way for new therapies and better liver health Metabolic dysfunction-associated steatohepatitis (MASH) is a liver disease ...