Monkey experiments hint at a "motivation brake" pathway between two brain regions. Manipulating it may lead to new treatments ...

The third Monday in January has earned the title of “Blue Monday,” widely regarded as the most miserable day of the year.

Researchers suggest that, from a clinical perspective, the findings provide mechanistic insight into motivational deficits central to psychiatric disorders.

Exercise’s positive effect on depression is well-known, but not how it produces its anti-depressant effects. After reviewing a broad range of studies into how depression and physical activity affect ...

Ever wonder why starting feels harder than finishing? Brain research shows stress can quietly block motivation before action ...

Researchers have discovered a break that could help ease a common symptom of depression. Discover more about it.

One of the key features of depression is the lack of motivation to do things that you know you should really do. For example, you may think that you don't have the motivation to exercise, or spend ...

At Stanford, a treatment that aims magnetic pulses at the brain is showing results for people with treatment-resistant ...

A recent research review shows that exercise may be nearly as effective as therapy in managing depression. However, experts ...

Researchers from Denmark have uncovered strong evidence that depression often appears years before Parkinson’s disease and ...

Most of us know the feeling: maybe it is making a difficult phone call, starting a report you fear will be criticized, or ...