Figure 3: Characterization of the split AAV vector heterodimerization by RT–PCR and DNA-PCR. There are many potential applications for using SAVE to carry large genes of therapeutic benefit for ...

An R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent ...

Scientists at Purdue University and the University of Minnesota have solved the three-dimensional structure of the central component of a biological "motor" that powers the DNA packaging system in a ...

A new study in the journal Human Gene Therapy indicates that DNA impurities derived from plasmid and host cell DNA are ...

The adenovirus vector is released with Pac I and then 293 cells are ... Several plaques are selected, expanded, HIRT DNA is analyzed, and virus lysates are sent to you for testing transgene expression ...

Viral protein is made intracellularly and the protein is processed via the endogenous MHC class I pathway. DNA vaccines. DNA vaccines favor a cell-mediated immune response. DNA plasmid vector ...

Some viruses need an intermediate organism, called a vector, to be transmitted from one type of host to another. Arthropods, such as mosquitoes and ticks, are often vectors for transmitting ...

Of note, the vector particles ... virus (FIV), and equine infectious anemia virus (EIAV) have also been developed. Because DNA flap structure formation during reverse transcription is a general ...

The team is now using that viral DNA map to explore how Y ... Human-to-human transmission of bubonic plague is rare, with the vector typically being 'flea-bitten' animals, like rats and dogs.

Circio and Entos have initiated a research collaboration that will involve joint development and in vivo delivery testing of ...

A new vector has been developed that integrates the Cre enzyme gene with its target DNA sequence, loxP, enabling the creation of Cre-loxP organisms in a single step.