An R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent ...

To achieve this, the team focused on two key aspects of CRISPR/Cas9 vector design: the promotor to drive Cas9 expression, and the nuclear localization signals (NLS) that direct the protein to the ...

R75W mutation in the gap junction β2 (GJB2) gene causes severe fragmentation of gap junction plaques, connecting adjacent ...

Congenital hearing loss refers to impaired auditory function that occurs due to genetic causes. GJB2 is the gene responsible ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

Human extracellular matrices can be edited in their composition using the CRISPR/Cas9 system, leading to materials exhibiting tailored regenerative capacities.

Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ... Dec. 13, 2024 — Microorganisms produce a wide variety of natural products that can be ...

CRISPR-Cas9 burst onto the broader scientific scene in 2012 when a team led by Jennifer Doudna showed that it could be modified to target and cut specific segments of DNA. The CRISPR half of the ...

ERS Genomics Limited ('ERS'), the CRISPR licensing company, and Jumpcode Genomics ('Jumpcode'), a life science tools company ...