and take a little snippet of them — about 40 nucleotides — that they integrate in a CRISPR array. The array is simply a DNA sequence of repetitive records that are formed iteratively and ...

Previously, Zhang's team had adapted bacterial CRISPR systems into ... in bacteria-infecting viruses. Sequences within each ...

The CRISPR arrays are composed of a repeated array of short sequences, each originating from and exactly matching a nucleic acid sequence that once invaded the host. Accompanying CRISPR sequences ...

With CRISPR-Cas9, the crRNA/tracrRNA sequence or an artificial guide RNA indicate where the DNA can be cut. It is relatively easy for scientists to produce different sequence variants from RNA ...

View Full Profile. Learn about our Editorial Policies. The ability of CRISPR gene-editing technology to safely modify human embryos has been cast into doubt after several recent papers described ...

The authors introduce SelectID, an approach combining CRISPR-guided targeting with methylation-sensitive labeling to identify proteins interacting with methylated repetitive sequences. They ...