A bacteriophage attaches itself to a susceptible bacterium and infects the host cell. Following infection, the bacteriophage hijacks the bacterium's cellular machinery to prevent it from producing ...

If the infecting phage is virulent, the infection follows a lytic cycle, or for temperate phages ... is a one-size-fits-all pre-defined formulation that consists of several bacteriophage strains, ...

Biliary tract infections (BTI), often linked to structural abnormalities like bile duct stones, pose significant treatment challenges due to drug-resistant bacteria like Pseudomonas aeruginosa. Phage ...

It is important to understand factors at play early in the infection cycle, when the phage finds and binds to bacterial cell surface, Antani said. This key initial step is called "phage attachment." ...

The researchers found, however, that some strains of bacteria appeared to be less vulnerable to bacteriophage infections than others and resisted the hijacking of their cell machinery by ...

The rising antibiotic resistance crisis poses a significant public health threat in hospitals and other settings, with infections resulting in millions of deaths in recent years. Scientists are now ...

In order to run PT service for clinicians, safe bacteriophage preparations for therapeutic use ... is beneficial in the treatment of severe (antibiotic-resistant) bacterial infections (in Finland) and ...