For instance, HOX antisense intergenic RNA (HOTAIR) is a lncRNA that regulates gene expression and chromatin dynamics.

In an article published in Molecular Therapy - Nucleic Acids, a team of researchers at Osaka University describe a strategy targeting one such mechanism, called RNA splicing. RNA splicing is the ...

Antisense oligonucleotides are short single ... RNA are double-stranded RNA molecules most notably involved in the RNA interference (RNAi) pathway where they interfere with gene expression by ...

BIIB080 is an antisense oligonucleotide therapy designed to target microtubule-associated protein tau mRNA and reduce the production of tau.

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions like a film editor rearranging scenes from the same footage to create ...

RNA therapeutics market is expanding, driven by advancements in gene therapy, personalized medicine, and RNA-based drug delivery, along with rising research in mRNA vaccines, antisense ...

Parallel quantification of large numbers of messenger RNA transcripts using microarray ... processes involved in the regulation of gene expression. This should allow new understanding of ...

proper gene expression and protein abundance. For each patient's genetic variant, Tang also designed antisense oligonucleotides—short, synthetic DNA strands that bind to and alter RNA or modify ...

Researchers at University of Tsukuba have developed "tomoseqr"—a new software tool that enables easy estimation of the ...

Scientists at Oak Ridge National Laboratory have developed the first-ever method of detecting ribonucleic acid, or RNA, ...

By using antisense oligonucleotides ... Similarly, cells splice RNA in different ways to produce a variety of proteins from a single gene, fine-tuning their function based on need.