Antisense oligonucleotides are short single-stranded oligonucleotides that bind to complementary RNA sequences. They can alter RNA and reduce, restore or modify protein expression. Small interfering ...

The discovery could pave the way for a groundbreaking RNA-based multi-cancer treatment. Alternative RNA splicing functions ...

They found their answer in antisense oligonucleotides (ASOs)-synthetic RNA fragments ... "It likely sequesters other RNA-binding proteins, creating an even more toxic environment for cancer cells." ...

LCGC International spoke with Daniel Meston and Dwight Stoll from Gustavus Adolphus College in St. Peter, Minnesota, USA, ...

Scientists from The Jackson Laboratory and UConn Health found that cancer cells disrupt poison exons, leading to tumor growth ...

However, our lab and others have discovered that TFs engage in a third type of interaction, which is binding RNA. In collaboration with the Batey Lab at CU, we have characterized the non-canonical RNA ...

Researchers have discovered that cancer cells suppress 'poison exons' -- genetic elements that act as an off switch for protein production -- in a key gene called TRA2 , promoting tumor growth. By ...

They found their answer in antisense oligonucleotides (ASOs ... “It likely sequesters other RNA-binding proteins, creating an even more toxic environment for cancer cells.” ...