Before leading the San Francisco 49ers to an overtime win over the Los Angeles Rams on Thursday night, Mac Jones made a terrifying discovery at the team's hotel. According to Dianna Russini of The Athletic,

Our 49ers vs. Rams predictions believe Matthew Stafford and the potent Los Angeles pass attack will pull away from San Francisco on Thursday, October 2, 2025. Free NFL picks for Week 5.

Rams blew a winnable game in OT against 49ers. Critical mistakes at key moments turned Stafford's 389-yard night into a bitter loss.

In his first full game as a 49er against the Rams, McCaffrey had a rushing touchdown, a receiving touchdown and even threw a touchdown pass.

When the Rams failed in a fourth-and-1 situation at the end of Thursday night's game against NFC West rival 49ers, they showed NFL fans that Mike Tomlin's choice to put instead of attempting to convert days earlier against the Vikings was a shrewd decision.

Brock Purdy remained on the 49ers injury report with toe and shoulder issues. Is Purdy going to play Thursday night against the Rams?

Should we expect a big day for the Bucs' receiving core? Can Quinshon Judkins go over 100 yards? And which AFC game could be low-scoring?